Kambo cleanse. A Kambo cleansing also known as a Kambo circle or Kambo ceremony, Kambo, vacina-do-sapo, or sapo, is a purge using skin secretions of the kambô, a species of frog. The ceremony involves burning an arm or leg and applying the kambo secretion. Kambo, which originated as a folk medicine practice among the Amazon indigenous peoples, is also administered as an alternative medicine treatment in the West, often as a cleanse or detox. Promoters claim that kambo helps with several illnesses or injuries.